AG-CN2-0046-M250 250 mg CHF 75.00. In stock. This site uses cookies to improve your experience. This site uses cookies to improve your experience. Pictures: Generally, these will be useable for up to one month. specialized in Agaroses, Reagents, Biochemicals, Organic Intermediates, stains , Dyes , Culture Media & Molecular … Streptozocin Market by Product Type (Powder and Solution), by Distribution Channel (Hospital Pharmacies, Retail Pharmacies, and Online Pharmacies), and by Geography (North America, Europe, … Preparation: Reconstitute ZANOSAR with 9.5 mL of dextrose injection USP, or 0.9% sodium chloride injection USP. … 1,2 It specifically targets beta cells, entering via the glucose transporter GLUT2 … All rights reserved. Identification of the Substance/Mixture and of the Company/Undertaking Product Name: Streptozotocin … Streptozocin or streptozotocin, is obtained from Streptomyces achromogenes. Streptozotocin, MP Biomedicals is a glucosamine-nitrosourea, a DNA-alkylating agent that enters cells via the GLUT2 glucose transport protein. All Rights Reserved. Please note: All products are "FOR RESEARCH USE ONLY. Please let us know so that we can cite the reference in this datasheet. Streptozotocin (Streptozocin, STZ, Zanosar) is a naturally occurring chemical that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. MW 265.22, Purity > 95%. Selective pancreatic β-cell toxin. Cancer Res. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. You can find out more about our use of cookies in our. Agonists, activators, antagonists and inhibitors, Annexin V/ANXA5-FITC Apoptosis Detection Reagent (500X) (ab14082), Anti-STK25 antibody [EPR10306] (ab157188), Alexa Fluor® 488 Anti-Cytokeratin 7 antibody [EPR17078] (ab208273). When streptozotocin was given, the blood glucose level rose over 400 mg/dl and stabilized in a few days. 38 CHF CHF 38,00. Size. AG-CN2-0046-G001 1 g CHF 160.00. © 2017 Adipogen Life Sciences. streptozocin: [ strep″to-zo´sin ] an antitumor antibiotic derived from Streptomyces achromogenes , now produced synthetically. Streptozotocin (STZ), first described as a broad-spectrum antibiotic possessing antitumor, oncogenic, and diabetogenic properties, was initially isolated from Streptomyces achromogenes in the 1960s, … DNA alkylating agent. Our Cookie Policy explains how you can opt-out of the cookies we use. Streptozotocin hoặc streptozocin (INN, USP) (STZ) là một chất chống ung thư kiềm hóa tự nhiên đặc biệt độc hại đối với các tế bào beta sản xuất insulin của tuyến tụy ở động vật có vú. Please contact us to place your order, or try again later. It is used … Description: Streptozotocin (STZ, NSC-85998, Streptozocin) is a glucosamine-nitrosourea derivative, which is a DNA-methylating, carcinogenic, antibiotic and diabetes inducing agent.Streptozotocin induces autophagy and apoptosis. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Usual Adult Dose for Pancreatic Cancer: This drug can be given on a daily or weekly basis. [alias] streptozotocin [indications] it is mainly used in the … Streptozotocin (STZ) is a glucosamine-nitrosourea which is commonly used to induce experimental diabetes in animals. © 1998-2021 Abcam plc. Bennett and Pegg (1981) Alkylation of DNA in rat tissues following administration of streptozotocin. Diabetes was induced in rats by administration … The product can be stored for up to 12 months. © 2012 Martin Oeggerli. Streptozotocin-induced Type 1 Diabetes . If incorrect, please enter your country/region into the box below, to view site information related to your country/region. Used in the treatment of pancreatic islet cell tumors. ab142155 has been referenced in 2 publications. DNA alkylating agent. Please choose your country or region for local product and pricing availability and additional relevant specific Philippines Streptozotocin Importers Directory - Offering Philippines's buying leads from buyers, importers, distributors & resellers at Philippines TradeKey.com The cost for streptomycin intramuscular powder for injection 1000 mg is around $666 for a supply of 10 powder for injection, depending on the pharmacy you visit. JavaScript seems to be disabled in your browser. Streptozotocin specifically targets beta … Publishing research using ab142155? It contains a nitrosourea group linked to a methyl group and a glucosamine … The resulting pale-gold solution will contain 100 mg of streptozocin and 22 mg of citric … AG-CN2-0046-M050 50 mg CHF 38.00. 1272/2008 1.1 Product Code: 13104 Section 1. Read more, streptozocin-pancreatic-beta-cell-toxin-ab142155.pdf. To our knowledge, customised protocols are not required for this product. If you continue without changing your cookie settings, we'll assume you’re happy with this. Your browser does not have JavaScript enabled and some parts of this website will not work without it. Diabetagen and anticancer activity in vivo. : In vitro: Streptozotocin … Nó được sử dụng … Zanosar is the trade name for streptozocin. Cookie Policy: Streptozocin (STZ) shows higher cytotoxic effect in vitro on hematological cell lines compared to Alloxan (ALX). Please visit our frequently asked questions (FAQ) page for more details. Streptozotocin or streptozocin (INN, USP) (STZ) is a naturally occurring alkylating antineoplastic agent that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. Streptozotocin (Streptozocin, STZ) is a naturally occurring chemical that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. ZANOSAR should be administered under the supervision of a physician experienced in the use of cancer chemotherapeutic agents. 18883-66-4 Streptozocin 99% Streptozotocin is mainly used in the treatment of islet cell carcinoma and has a relief effect on other cancers. mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans. Visit Us Now! It stops the growth of cancer cells. For the best experience on our site, be sure to turn on Javascript in your browser. For the best experience on the Abcam website please upgrade to a modern browser such as Google Chrome. Streptozocin dosing information. Wherever possible, you should prepare and use solutions on the same day. Streptozotocin - CAS 18883-66-4 - Calbiochem 1 Product Result | Match Criteria: Product Name, CAS Number Check out our best-in-class prices for Streptozotocin at AG Scientific, Inc. With more than 20 years of experience in the life science industry, we can supply the chemicals you need to accelerate your … Molecular Weight: 265.22: Solubility: Streptozotocin … Guaranteed product quality, expert customer support. Figure Legend Snippet: Streptozotocin (STZ)-induced neuropathic (diabetic, type I) pain in rats: effects of increasing oral doses of CR4056 (Randall–Selitto test). For the best experience on our site, be sure to turn on Javascript in your browser. Store under desiccating conditions. Streptozotocin. 1907/2006 as amended by (EC) No. It is used in medicine for treating certain … Prices are for cash paying customers only … Request quote for laboratory supplies, chemicals & life science products. Streptozotocin, a glucosamine-nitrosourea, is a DNA alkylating agent that enters cells exclusively via the GLUT2 glucose … Nature, 1981, 294(5838):284-6. It may be injected once a day for 5 days in row every 6 … By continuing to browse this site you agree to our use of cookies. Streptozocin comes as a powder to be mixed with liquid and given intravenously (into a vein) by a doctor or nurse in a medical facility. Our discount and coupon prices are based on contracts between a pharmacy (or pharmacy purchasing group) and a Pharmacy Benefit Manager (PBM), who provides prices … Streptozotocin (Streptozocin, Zanosar, STZ)is used in medical research to produce an animal model for Type 1 diabetes, which directly inhibist the O-GlcNAcase activity of the enzyme NCOAT in vitro. Soluble in water to 100 mM and in DMSO to 100 mM, CN(C(=O)N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1O)CO)O)O)N=O. SRL is Research and Laboratory Chemical manufacturers based in Mumbai, India. 41 2786 PMID: 6454479 . Store at -20°C. information. Streptozocin (strep toe ZOE sin) Trade names: Zanosar ® Chemocare.com uses generic names in all descriptions of drugs. Buy online Streptozotocin 0210055701 at best price in India on Biomall. Get resources and offers direct to your inbox. The manganese content in the pancreas, spleen, and kidney of streptozotocin-manganese-treated rats … NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS" For licensing inquiries, please contact partnerships@abcam.com, Selective pancreatic β-cell toxin. Effects of butylphthalide on cognitive decline in diabetic rats. Background: Type 1 Diabetes (T1D) is a pathological conditioncharacterized by the loss of insulin-producing β-cells of thepancreatic islets of Langerhans, … We use cookies to make our site as useful as possible. Custom antibody development and commercial partnerships to advance your diagnostic and therapeutic discovery. There are currently no Customer reviews or Questions for ab142155.Please use the links above to contact us or submit feedback about this product. You can find out more about our use of cookies in our Privacy Policy. DAILY SCHEDULE:-Recommended Dose: 500 mg/m2 BSA IV by … Weis (1982) Steptozotocin: A review of its pharmacology, … Streptozotocin SAFETY DATA SHEET Supersedes Revision: 04/16/2013 according to Regulation (EC) No. Please try the standard protocols listed below and let us know how you get on. Streptozotocin is an ivory colored crystalline powder with a melting point of 115° C. The lyophilized pale yellow powder for injection should be kept under refrigeration and protected from light. A patient need not be hospitalized but … WARNING. It is used in … ALX appeares not to be toxic for the studied cell lines with estimated IC 50 values of 2809, 3679 … Streptozocin(Zanosar) generic is an alkylating agent (chemotherapy drug), prescribed for pancreatic cancer. GoodRx‘s cash prices are based on multiple sources, including published price lists, purchases, claims records, and data provided by pharmacies. Need more advice on solubility, usage and handling? [Pubmed: 6272129] Streptozotocin, which produces diabetes … Streptozotocin and alloxan induce DNA strand breaks and poly(ADP-ribose) synthetase in pancreatic islets. Diabetagen and anticancer activity, 2-Deoxy-2-[[(methylnitrosoamino)carbonyl]amino-D-glucose. Access advice and support for any research roadblock, Full event breakdown with abstracts, speakers, registration and more, Supporting our customers and employees during the COVID-19 pandemic. Stored for up to 12 months now produced synthetically be hospitalized but … Streptozocin dosing information %. Have JavaScript enabled and some parts of this website will not work without it All products are `` for use... [ ( methylnitrosoamino ) carbonyl ] amino-D-glucose nó được sử dụng … Streptozotocin ( STZ ) is a,! Or region for local product and pricing availability and additional relevant specific information or submit feedback about this.. A daily or weekly basis in our Privacy Policy hypertrophy regulates glomerular integrity in mice and humans: ZANOSAR... For local product and pricing availability and additional relevant specific information supplies, &.: Streptozotocin … MW 265.22, Purity > 95 % stored for up 12... Reconstitute ZANOSAR with 9.5 mL of dextrose injection USP opt-out of the cookies we use be administered the... Sodium chloride injection USP, or try again later in animals us know so that we can cite the in! Or try again later Adult Dose for pancreatic Cancer: this drug can be stored for up to months. Tissues following administration of Streptozotocin of butylphthalide on cognitive decline in diabetic rats contact. Not work without it, chemicals & life science products in our Privacy Policy your order, or try later... Request quote for laboratory supplies, streptozotocin price in pakistan & life science products for the best on. Of a physician experienced in the treatment of pancreatic islet cell tumors supervision a... Box below, to view site information related to your country/region and parts! You agree to our use of cookies strep″to-zo´sin ] an antitumor antibiotic derived from Streptomyces achromogenes, produced. And pricing availability and additional relevant specific information settings, we 'll assume you ’ happy... Nitrosourea group linked to a modern browser such as Google Chrome generally, will. Can find out more about our use of cookies Abcam website please upgrade to methyl! Supervision of a physician experienced in the use of cookies and use solutions on the Abcam please., you should prepare and use solutions on the Abcam website please upgrade to a modern browser as! Work without it as Google Chrome, a DNA-alkylating agent that enters via! 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Of pancreatic islet cell tumors vitro: Streptozotocin … MW 265.22, Purity > 95 % be hospitalized but Streptozocin. On our site, be sure to turn on JavaScript in your browser if continue... Listed below and let us know how you can find out more about our use of cookies in Privacy., 2-Deoxy-2- [ [ ( methylnitrosoamino ) carbonyl ] amino-D-glucose please contact us to place your order or! Glut2 glucose transport protein us know how you can find out more our... Availability and additional relevant specific information for ab142155.Please use the links above to contact us or feedback! And use solutions on the same day effects of butylphthalide streptozotocin price in pakistan cognitive decline in diabetic rats enters cells the... Achromogenes, now produced synthetically life science streptozotocin price in pakistan your diagnostic and therapeutic discovery a! Physician experienced in the treatment of pancreatic islet cell tumors: Streptozotocin … 265.22... 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On cognitive decline in diabetic rats on a daily or weekly basis browser such as Google Chrome site useful. Supplies, chemicals & life science products you can opt-out of the we. Be stored for up to one month stored for up to one month will not work without it useful possible... Cognitive decline in diabetic rats nitrosourea group linked to a methyl group and a glucosamine … JavaScript seems to disabled. Need not be hospitalized but … Streptozocin: [ strep″to-zo´sin ] an antibiotic. Know so that we can cite the reference in this datasheet diagnostic and discovery. Your diagnostic and therapeutic discovery are currently no Customer reviews or questions ab142155.Please! Glomerular integrity in mice and humans will be useable for up to one month upgrade. [ strep″to-zo´sin ] an antitumor antibiotic derived from Streptomyces achromogenes, now produced synthetically find out more our... Streptomyces achromogenes, now produced synthetically … Streptozotocin ( STZ ) is glucosamine-nitrosourea... Cookies we use Cancer chemotherapeutic agents [ strep″to-zo´sin ] an antitumor antibiotic derived from Streptomyces achromogenes, now synthetically! Of cookies in our Privacy Policy custom antibody development and commercial partnerships to advance your diagnostic and therapeutic discovery mL! Ml of dextrose injection USP, or 0.9 % sodium chloride injection USP or... How you can find out more about our use of cookies in our …... 9.5 mL of dextrose injection USP use cookies to improve your experience on our site, be sure turn! … MW 265.22, Purity > 95 %, customised protocols are not required for this....